Epidemiologic Studies of Beta Agonists and Asthma Deaths

Meta-analysis: effect of long-acting beta-agonists on severe asthma exacerbations and asthma-related deaths.

BACKGROUND Long-acting beta-agonists may increase the risk for fatal and nonfatal asthma exacerbations. PURPOSE To assess the risk for severe, life-threatening, or fatal asthma exacerbations associated with long-acting beta-agonists. DATA SOURCES English- and non-English-language searches of MEDLINE, EMBASE, and Cochrane databases; the U.S. Food and Drug Administration Web site; and referen...

Review: long-acting beta-agonists increase severe asthma exacerbations and asthma-related deaths in children and adults.

Safety of Long - Acting Beta - Agonists in Asthma ASTHMA THERAPY

THE EUROPEAN JOURNAL OF RESPIRATORY MEDICINE VOL I ISSUE I Although there was no attempt to determine degree of adherence with ICS at randomisation or persistence in their use during the course of the study, no significant differences were seen for primary events and asthma-related events, including deaths in the total population of patients receiving ICS at baseline. However, in the total popu...

postnatal studies of bats (pipistrellus kuhlii and miniopterus schreibersii) & histomorphology and histochemistry studies of organs and diseases of (neurergus microspilotus and n. kaiseri)

1. to determine whether difference in birth body mass influenced growth performance in pipistrellus kuhlii we studied a total of 12 captive-born neonates. bats were assigned to two body mass groups: light birth body mass (lbw: 0.89 ± 0.05, n=8) and heavy birth body mass (hbw: 1.35 ± 0.08, n=4). heavier body mass at birth was associated with rapid postnatal growth (body mass and forearm length) ...

Addition of intravenous beta(2)-agonists to inhaled beta(2)-agonists for acute asthma.

BACKGROUND Inhaled beta-agonist therapy is central to the management of acute asthma. This review evaluates the benefit of an additional use of intravenous beta(2)-agonist agents. OBJECTIVES To determine the benefit of adding intravenous (IV) beta(2)-agonists to inhaled beta(2)-agonist therapy for acute asthma treated in the emergency department. SEARCH METHODS Randomised controlled trials ...